Highlights from Fall Clinical Dermatology Conference 2025


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New Topical and Systemic Therapies Are Shifting the Paradigm for the Management of Chronic Hand Eczema

Emerging therapies are changing the way dermatologists think about the management of chronic hand eczema (CHE), while providing them with more options that can help achieve stable, long-term control of the disease. While CHE management traditionally centered on control of symptoms and flares, the development of novel agents that target the underlying mechanisms of CHE may provide durable improvements in symptoms and quality of life. 

October 27, 2025

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Effective Long-Term Management Is an Unmet Need for Patients with Chronic Hand Eczema

The toolbox for the treatment of chronic hand eczema (CHE) has continued to expand, with targeted therapies setting new standards for disease control. Nevertheless, findings from a survey of healthcare providers, presented at the 2025 Fall Clinical Conference in Las Vegas, revealed that many patients with moderate-to-severe CHE continue to struggle with inadequate management of their disease. 

October 27, 2025

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Tralokinumab Passes Real-World Test in the Treatment of Moderate-to-Severe Atopic Dermatitis

Tralokinumab improved quality of life outcomes related to itch, sleep, and treatment satisfaction for individuals with moderate-to-severe atopic dermatitis (AD) followed for 52 weeks in a real-world study, regardless of prior dupilumab use. The final analysis of the prospective longitudinal study enrolling U.S.-based patients with AD from the Adbry® AdvocateTM Program was presented in a poster session at the 2025 Fall Clinical Dermatology Conference, in Las Vegas. 
 

October 27, 2025

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From Hands to Pockets: the High Cost of Managing Chronic Hand Eczema

The financial burden related to the costs of managing chronic hand eczema (CHE), which is often underestimated, represents a source of psychological distress and may be a barrier to care for individuals living with this skin disease. Findings from a study presented at the 2025 Fall Clinical Dermatology Conference in Las Vegas, Nevada showed that living with CHE translates into significant economic strain due to high healthcare resource utilization and out-of-pocket costs.
 

October 28, 2025

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 Long-Term Data Reinforce Safety of Upadacitinib in Treating Atopic Dermatitis in Oral Contraceptive Users 

Women with atopic dermatitis (AD) who take oral contraceptive pills (OCPs) need not write off upadacitinib as a treatment option, according to pooled data from several phase 3 randomized clinical trials, which revealed a favorable benefit–risk profile of the Janus kinase (JAK) inhibitor in this population. 

October 28, 2025

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Social Determinants of Health Shape the Course of Chronic Hand Eczema

Sociodemographic factors and comorbidities may influence the course and severity of chronic hand eczema (CHE), according to findings from the CHECK study of U.S.-based adults with CHE presented during a poster session at the 2025 Fall Clinical Dermatology Conference in Las Vegas. Understanding individual variations can guide treatment and prevention strategies and may ultimately minimize gaps in care for people with CHE. 

October 28, 2025

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