Supplemental educational content
A Hereditary Cancer Testing Patient Guide
A guide to genetic testing for hereditary cancer: share with your patients!
Read MoreA Provider Reference Guide for Breast and Gynecological Cancers
Hereditary Cancer Risk Assessment
Read MorePatient blog about breast cancer and “previvorship”:
A Different Kind of Patient: Emily Huebsch Empowers Herself and Others Against Breast Cancer
Read MoreGreater than the Sum of its Parts: Gene-Disease Validity and Breast Cancer
This article explores the concept of gene-disease validity (GDV) in the context of breast cancer, emphasizing the complexity of establishing genetic associations in a common disease with multifactorial causes. It highlights the rigorous evidence—both clinical and experimental—required to confirm whether specific gene variants truly contribute to hereditary breast cancer risk. The piece underscores the importance of replication, large datasets, and functional data to avoid premature or inaccurate gene-disease links.
Read MoreWEBINAR: The Whole is Greater than the Sum of its Parts: Understanding gene-disease validity for breast cancer genes
This talk will focus on the evaluation of gene-disease associations (also known as gene-disease validity) for genes potentially implicated in hereditary breast cancer. We will review the topic of gene-disease validity, including background and definitions surrounding this topic. There will be a specific focus on the evaluation of gene-disease associations for breast cancer-associated genes, with an emphasis on the challenges associated with these assessments and the relationship of these assessments to clinical utility.
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