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Test Your Knowledge

Breast Cancer Awareness Month Home Page
  1. Approximately how many breast cancer cases diagnosed in the United States each year can be linked to hereditary causes?
  2. Pathogenic variants of which of the following genes are strongly associated with breast cancer (i.e., high-penetrance breast cancer susceptibility genes)? (check all that apply)
  3. A 55-year-old woman has been newly diagnosed with stage 1 breast cancer. According to the recent ASCO-SSO guideline on germline mutation testing in breast cancer,1 should this patient be offered BRCA1/2 testing?
  4. According to the recent ASCO-SSO guideline on germline mutation testing in breast cancer,1 which of the following risk factors have been shown to help inform breast cancer medical and surgical treatment planning? (choose all that apply)
  5. Breast cancer previvors – individuals with known hereditary risk for breast cancer but who have not yet developed cancer – should be offered which of the following?

Reference

  1. Bedrosian I, et al. Germline testing in patients with breast cancer: ASCO–Society of Surgical Oncology Guideline. J Clin Oncol. 2024;42:584-604. DOI:10.1200/JCO.23.02225
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